IMSI Treatment
With IMSI (Intracytoplasmic Morphologically-selected Sperm Injection) treatment, a selected sperm is injected into the ova (female egg) directly, and then incubated before being returned to the uterus.
What is IMSI?

IMSI is an advanced method over ICSI to improve embryo quality. When sperm morphology is very poor, and the resulting embryos from previous ICSIs have been poor and not resulted in a pregnancy, IMSI is the next option to consider. IMSI, which entails the selection of sperm at 200 to 400 times larger magnification than standard ICSI, enables the embryologist to closely scrutinise the sperm morphology in more detail.

A ‘hero’ sperm is then selected and injected directly into the ova.

IMSI has been shown to improve embryo quality, reduce miscarriages rate and increase chances of an ongoing pregnancy.

The process & what to expect

The process of IMSI does not require any additional procedures on your side; an IMSI cycle will continue just as an ICSI cycle would. The IMSI cycle only changes some of the processes within the laboratory. Different lab consumables are used and the sperm selection technique under the microscope are different to ICSI. Notably, the only difference on your behalf with regards to IMSI is that it is an additional cost, and that the final outcome of the cycle might hopefully be more successful than past cycles.

Is IMSI right for you?

The indications for IMSI include:

  • Severe male factor infertility (poor morphology)
  • Recurrent failed ICSI cycles
  • Failed blastulation
  • Poor fertilization within previous ICSI cycles

Q:Is there an extra cost involved with IMSI, when compared to ICSI?
A: Yes, there is an additional cost for IMSI. The additional cost is R3900, however, this cost may vary.

Q: Does IMSI guarantee success?
A: There are unfortunately no ‘guarantees’ when it comes to fertility treatment, making it one of the most difficult journeys one can go through. However, with that said, IMSI has been proven by some studies to be more beneficial than ICSI as an indication treatment, but there are still no guarantees.

Q: What are the risks of IMSI?
A: It is not known if there are risks of IMSI over and above those known from ICSI.

Still have questions?
Should you require any additional information, please contact the clinic directly and one of our friendly staff members will happily assist you.